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Implantable Pulmonary Artery Banding for Congenital Heart Disease

Congenital heart diseases (CHD) affect nearly 1% of – or about 40,000 – births per year in the United States. Among them, about 25% of newborns are in critical condition and need surgery or other procedures in the first year of life. Pulmonary artery banding (PAB) is a palliative surgical operation for patients with congenital heart disease suffering from pulmonary hypertension. This surgery is an invasive procedure to secure a surgical band around the pulmonary artery to regulate blood flow through the vessel. As the infant grows the band must to be readjusted which requires subsequent procedures.

3D view of the telemetrically adjustable PAB device.Schematic 3D view of the telemetrically adjustable PAB device.

 

The objective of this work is to design, fabricate, and test an advanced implantable pulmonary artery banding (PAB) system for infants suffering from congenital heart disease or other patients.  The proposed design aims to address the need for a bio-compatible and compact artery banding (< 1mm diameter) system capable of telemetric adjustment to reduce to the need for follow up surgeries post placement.

 

This novel battery-less device utilizes radio frequency (RF) excitation for wireless energy transfer and a pair of magnetically-driven micro-actuators with suspended doubly-clamped polymeric beams for clamping. Multiphysics finite element simulations are used for design and optimization. The proposed implant is less than 1 cubic centimeter in size and has the ability to achieve 50% artery restriction. The PAB discussed in this paper is suitable for small infants less than 3kg in weight. Moreover, due to its small size, the device enables in vivo medical research on lab animals.

 

© Prof. Nima Ghalichechian's Group

Related Paper

 B. P. Lough, B. Ghassemiparvin, and N. Ghalichechian, “RF Micro-Electro-Mechanical Pulmonary Artery Banding for Congenital Heart Diseases”, IEEE 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Orlando, FL, USA, August 17-20, 2016.